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Chemistry of Biotin–Streptavidin and the Growing Concern of an Emerging Biotin Interference in Clinical Immunoassays

[Image: see text] Overconsumption of biotin (5–100 mg daily) as a supplement by the general population poses a significant problem for clinical immunoassays (IAs) based on biotin–streptavidin (SA) interactions. This affinity pair has been exploited in immunoassays because of its avidity, sensitivity...

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Detalhes bibliográficos
Publicado no:ACS Omega
Main Authors: Luong, John H. T., Vashist, Sandeep K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2019
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6963918/
https://ncbi.nlm.nih.gov/pubmed/31956746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.9b03013
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