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Functional Loop Dynamics of the Streptavidin-Biotin Complex

Accelerated molecular dynamics (aMD) simulation is employed to study the functional dynamics of the flexible loop(3-4) in the strong-binding streptavidin-biotin complex system. Conventional molecular (cMD) simulation is also performed for comparison. The present study reveals the following important...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Song, Jianing, Li, Yongle, Ji, Changge, Zhang, John Z. H.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4298722/
https://ncbi.nlm.nih.gov/pubmed/25601277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep07906
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