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Countering Gram-Negative Antibiotic Resistance: Recent Progress in Disrupting the Outer Membrane with Novel Therapeutics

Gram-negative bacteria shield themselves from antibiotics by producing an outer membrane (OM) that forms a formidable permeability barrier. Multidrug resistance among these organisms is a particularly acute problem that is exacerbated by the OM. The poor penetrance of many available antibiotics prev...

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Detalhes bibliográficos
Publicado no:Antibiotics (Basel)
Main Authors: Lehman, Kelly M., Grabowicz, Marcin
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6963605/
https://ncbi.nlm.nih.gov/pubmed/31554212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antibiotics8040163
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