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Synthesis and Biological Evaluation of Lipophilic Nucleoside Analogues as Inhibitors of Aminoacyl-tRNA Synthetases

Emerging antibiotic resistance in pathogenic bacteria and reduction of compounds in the existing antibiotics discovery pipeline is the most critical concern for healthcare professionals. A potential solution aims to explore new or existing targets/compounds. Inhibition of bacterial aminoacyl-tRNA sy...

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Detalhes bibliográficos
Publicado no:Antibiotics (Basel)
Main Authors: Nautiyal, Manesh, Gadakh, Bharat, De Graef, Steff, Pang, Luping, Khan, Masroor, Xun, Yi, Rozenski, Jef, Van Aerschot, Arthur
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6963541/
https://ncbi.nlm.nih.gov/pubmed/31600972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antibiotics8040180
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