PTCy ameliorates GVHD by restoring regulatory and effector T-cell homeostasis in recipients with PD-1 blockade

Graft-versus-host disease (GVHD) after allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a significant cause of morbidity and mortality. Regulatory T cells (Tregs) are critical mediators of immune tolerance after allo-HSCT. Clinical studies have indicated that programmed cell death 1...

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Ikegawa, Shuntaro, Meguri, Yusuke, Kondo, Takumi, Sugiura, Hiroyuki, Sando, Yasuhisa, Nakamura, Makoto, Iwamoto, Miki, Maeda, Yoshinobu, Matsuoka, Ken-ichi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2019
Assuntos:
Transplantation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6963247/
https://ncbi.nlm.nih.gov/pubmed/31821459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019000134
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