Melatonin alleviates hypoxia-induced cardiac apoptosis through PI3K/Akt pathway

Hypoxia-induced apoptosis is an inevitable problem in cyanotic congenital heart disease. In the present study, we investigated effects of melatonin on hypoxic cardiomyocytes in vitro and in vivo, and explored its underlying mechanism. H9C2 cells were subjected to hypoxia for 48 hours. Mice were subj...

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Bibliografiske detaljer
Udgivet i:Int J Clin Exp Pathol
Main Authors: Luo, Gui-Ping, Jian, Zhao, Ma, Rui-Yan, Cao, Zhe-Zhe, Zhu, Yun, Zhu, Yu, Tang, Fu-Qin, Xiao, Ying-Bin
Format: Artigo
Sprog:Inglês
Udgivet: e-Century Publishing Corporation 2018
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6963099/
https://ncbi.nlm.nih.gov/pubmed/31949670
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