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Melatonin alleviates hypoxia-induced cardiac apoptosis through PI3K/Akt pathway

Hypoxia-induced apoptosis is an inevitable problem in cyanotic congenital heart disease. In the present study, we investigated effects of melatonin on hypoxic cardiomyocytes in vitro and in vivo, and explored its underlying mechanism. H9C2 cells were subjected to hypoxia for 48 hours. Mice were subj...

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Bibliografiska uppgifter
I publikationen:Int J Clin Exp Pathol
Huvudupphovsmän: Luo, Gui-Ping, Jian, Zhao, Ma, Rui-Yan, Cao, Zhe-Zhe, Zhu, Yun, Zhu, Yu, Tang, Fu-Qin, Xiao, Ying-Bin
Materialtyp: Artigo
Språk:Inglês
Publicerad: e-Century Publishing Corporation 2018
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6963099/
https://ncbi.nlm.nih.gov/pubmed/31949670
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