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MiR-106a-5p promotes 5-FU resistance and the metastasis of colorectal cancer by targeting TGFβR2

Background: Colorectal cancer (CRC) is the third leading cause of cancer-related deaths. 5-Fluorouracil (5-FU)-based chemotherapy has always been the first-line treatment. However, development of 5-FU resistance seriously affects its curative effect. The aim of this study was to elucidate the molecu...

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Detalhes bibliográficos
Publicado no:Int J Clin Exp Pathol
Main Authors: Liu, Jian, Huang, Yanqin, Wang, Hongqian, Wu, Denghai
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6963073/
https://ncbi.nlm.nih.gov/pubmed/31949649
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