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TGF-β upregulates miR-181a expression to promote breast cancer metastasis
Late-stage breast cancer metastasis is driven by dysregulated TGF-β signaling, but the underlying molecular mechanisms have not been fully elucidated. We attempted to recapitulate tumor and metastatic microenvironments via the use of biomechanically compliant or rigid 3D organotypic cultures and com...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3533297/ https://ncbi.nlm.nih.gov/pubmed/23241956 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI64946 |
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