The protective effect of the Rho-kinase inhibitor hydroxyfasudil on propofol-induced hippocampal neuron apoptosis in neonatal rats

Propofol is widely applied for anesthesia induction in pediatric patients. However, accumulating evidence has proved that propofol is neurotoxic to the immature or developing brain. In the present study, we found that hydroxyfasudil, a specific inhibitor of Rho kinase, alleviated the apoptotic neuro...

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Vydáno v:Int J Clin Exp Pathol
Hlavní autoři: Li, Xuze, Huang, Lining, Zhao, Zhifang, Bo, Lijun, Kang, Rongtian, Yang, Jiaojiao, Dong, Zhenming
Médium: Artigo
Jazyk:Inglês
Vydáno: e-Century Publishing Corporation 2018
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6962995/
https://ncbi.nlm.nih.gov/pubmed/31949854
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