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Synergistic activation of mitochondrial metabolism and the glutathione redox couple protects HepG2 hepatocarcinoma cells from palmitoylcarnitine-induced stress

Fatty acid stress can have divergent effects in various cancers. We explored how metabolic and redox flexibility in HepG2 hepatocarcinoma cells mediates protection from palmitoylcarnitine. HepG2 cells, along with HCT 116 and HT29 colorectal cancer cells were incubated with 100 μM palmitoylcarnitine...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Am J Physiol Cell Physiol
Prif Awduron: Turnbull, Patrick C., Dehghani, Ali C., Theriau, Christopher F., Connor, Michael K., Perry, Christopher G. R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Physiological Society 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6962524/
https://ncbi.nlm.nih.gov/pubmed/31618075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00366.2019
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