Identification of a novel selective and potent inhibitor of glycogen synthase kinase-3

Glycogen synthase kinase-3 (GSK-3) is a multitasking protein kinase that regulates numerous critical cellular functions. Not surprisingly, elevated GSK-3 activity has been implicated in a host of diseases including pathological inflammation, diabetes, cancer, arthritis, asthma, bipolar disorder, and...

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Pubblicato in:Am J Physiol Cell Physiol
Autori principali: Noori, Mahboubeh S., Bhatt, Pooja M., Courreges, Maria C., Ghazanfari, Davoud, Cuckler, Chaz, Orac, Crina M., McMills, Mark C., Schwartz, Frank L., Deosarkar, Sudhir P., Bergmeier, Stephen C., McCall, Kelly D., Goetz, Douglas J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2019
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6962522/
https://ncbi.nlm.nih.gov/pubmed/31553649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00061.2019
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