Phenylmethimazole and a thiazole derivative of phenylmethimazole inhibit IL-6 expression by triple negative breast cancer cells

Inhibition of interleukin–6 (IL-6) holds significant promise as a therapeutic approach for triple negative breast cancer (TNBC). We previously reported that phenylmethimazole (C10) reduces IL-6 expression in several cancer cell lines. We have identified a more potent derivative of C10 termed COB-141...

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Publicat a:Eur J Pharmacol
Autors principals: Noori, Mahboubeh S., O'Brien, John D., Champa, Zachary J., Deosarkar, Sudhir P., Lanier, Olivia L., Qi, Chunyan, Burdick, Monica M., Schwartz, Frank L., Bergmeier, Stephen C., McCall, Kelly D., Goetz, Douglas J.
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5461878/
https://ncbi.nlm.nih.gov/pubmed/28343970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2017.03.049
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