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A continuous evolution system for contracting the host range of bacteriophage T7

Bacteriophage T7 is an intracellular parasite that recognizes its host via its tail and tail fiber proteins, known as receptor-binding proteins (RBPs). The RBPs attach to specific lipopolysaccharide (LPS) features on the host. Various studies have shown expansion of the phage’s host range via mutati...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Holtzman, Tzvi, Globus, Rea, Molshanski-Mor, Shahar, Ben-Shem, Adam, Yosef, Ido, Qimron, Udi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6962156/
https://ncbi.nlm.nih.gov/pubmed/31941920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-57221-0
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