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Optimizing DNA transduction by selection of mutations that evade bacterial defense systems
We recently developed a platform where phage-transducing particles optimize DNA delivery to a wide range of hosts. Here, we use this platform to optimize DNA transduction into hosts that naturally restrict specific DNA sequences. We first show that a specific plasmid is restricted for transduction i...
Enregistré dans:
| Publié dans: | RNA Biol |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Taylor & Francis
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6546373/ https://ncbi.nlm.nih.gov/pubmed/30146918 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2018.1514235 |
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