C4BP-IgM protein as a therapeutic approach to treat Neisseria gonorrhoeae infections

Gonorrhea is a sexually transmitted infection with 87 million new cases per year globally. Increasing antibiotic resistance has severely limited treatment options. A mechanism that Neisseria gonorrhoeae uses to evade complement attack is binding of the complement inhibitor C4b-binding protein (C4BP)...

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Bibliografiske detaljer
Udgivet i:JCI Insight
Main Authors: Bettoni, Serena, Shaughnessy, Jutamas, Maziarz, Karolina, Ermert, David, Gulati, Sunita, Zheng, Bo, Mörgelin, Matthias, Jacobsson, Susanne, Riesbeck, Kristian, Unemo, Magnus, Ram, Sanjay, Blom, Anna M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2019
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Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6962029/
https://ncbi.nlm.nih.gov/pubmed/31661468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.131886
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