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Proteasome inhibition preserves longitudinal growth of denervated muscle and prevents neonatal neuromuscular contractures

Muscle contractures are a prominent and disabling feature of many neuromuscular disorders, including the 2 most common forms of childhood neurologic dysfunction: neonatal brachial plexus injury (NBPI) and cerebral palsy. There are currently no treatment strategies to directly alter the contracture p...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:JCI Insight
Hauptverfasser: Nikolaou, Sia, Cramer, Alyssa A.W., Hu, Liangjun, Goh, Qingnian, Millay, Douglas P., Cornwall, Roger
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6962017/
https://ncbi.nlm.nih.gov/pubmed/31661460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.128454
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