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FGF23 expression is stimulated in transgenic α-Klotho longevity mouse model
Observations in transgenic α-Klotho (Kl) mice (Kl(Tg)) defined the antiaging role of soluble Klotho (sKL(130)). A genetic translocation that elevates sKL levels in humans is paradoxically associated with increased circulating fibroblast growth factor 23 (FGF23) levels and the potential of both membr...
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| Izdano u: | JCI Insight |
|---|---|
| Glavni autori: | , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Clinical Investigation
2019
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6962016/ https://ncbi.nlm.nih.gov/pubmed/31801907 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.132820 |
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