Mevastatin promotes healing by targeting caveolin-1 to restore EGFR signaling

Diabetic foot ulcers (DFUs) are a life-threatening disease that often results in lower limb amputations and a shortened life span. Current treatment options are limited and often not efficacious, raising the need for new therapies. To investigate the therapeutic potential of topical statins to resto...

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Detalles Bibliográficos
Publicado en:JCI Insight
Autores principales: Sawaya, Andrew P., Jozic, Ivan, Stone, Rivka C., Pastar, Irena, Egger, Andjela N., Stojadinovic, Olivera, Glinos, George D., Kirsner, Robert S., Tomic-Canic, Marjana
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2019
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6962014/
https://ncbi.nlm.nih.gov/pubmed/31661463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.129320
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