Topical mevastatin promotes wound healing by inhibiting the transcription factor c-Myc via the glucocorticoid receptor and the long non-coding RNA Gas5

Diabetic foot ulcers (DFUs), a life-threatening complication of diabetes mellitus, have limited treatment options, often resulting in amputations. HMG-CoA reductase inhibitors such as statins are cholesterol-reducing agents that may provide a new therapeutic option. Statins target the cholesterol pa...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Foilsithe in:J Biol Chem
Main Authors: Sawaya, Andrew P., Pastar, Irena, Stojadinovic, Olivera, Lazovic, Sonja, Davis, Stephen C., Gil, Joel, Kirsner, Robert S., Tomic-Canic, Marjana
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2018
Ábhair:
Molecular Bases of Disease
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5787818/
https://ncbi.nlm.nih.gov/pubmed/29158265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.811240
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!

Míreanna Comhchosúla