Liganded T3 receptor β2 inhibits the positive feedback autoregulation of the gene for GATA2, a transcription factor critical for thyrotropin production

The serum concentration of thyrotropin (thyroid stimulating hormone, TSH) is drastically reduced by small increase in the levels of thyroid hormones (T3 and its prohormone, T4); however, the mechanism underlying this relationship is unknown. TSH consists of the chorionic gonadotropin α (CGA) and the...

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Publicado en:PLoS One
Autores principales: Hirahara, Naoko, Nakamura, Hiroko Misawa, Sasaki, Shigekazu, Matsushita, Akio, Ohba, Kenji, Kuroda, Go, Sakai, Yuki, Shinkai, Shinsuke, Haeno, Hiroshi, Nishio, Takuhiro, Yoshida, Shuichi, Oki, Yutaka, Suda, Takafumi
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2020
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6961892/
https://ncbi.nlm.nih.gov/pubmed/31940421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0227646
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