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STING is dispensable during KSHV infection of primary endothelial cells

During DNA virus infections, detection of cytosolic DNA by the cGAS-STING pathway leads to activation of IFN-β. Kaposi’s Sarcoma Herpesvirus (KSHV), an oncogenic DNA virus, is the etiological agent of Kaposi’s Sarcoma, an endothelial cell (EC)-based tumor. To investigate the role of STING during KSH...

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Detalhes bibliográficos
Publicado no:Virology
Main Authors: Vogt, Daniel, Zaver, Shivam, Ranjan, Alice, DiMaio, Terri, Gounder, Anshu P., Smith, Jason G., Lagunoff, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6961814/
https://ncbi.nlm.nih.gov/pubmed/31928996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2019.11.012
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