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Itaconate modulates tricarboxylic acid and redox metabolism to mitigate reperfusion injury
OBJECTIVES: Cerebral ischemia/reperfusion (IR) drives oxidative stress and injurious metabolic processes that lead to redox imbalance, inflammation, and tissue damage. However, the key mediators of reperfusion injury remain unclear, and therefore, there is considerable interest in therapeutically ta...
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| Publicado no: | Mol Metab |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6961711/ https://ncbi.nlm.nih.gov/pubmed/32029222 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2019.11.019 |
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