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Human rDNA copy number is unstable in metastatic breast cancers

Chromatin-mediated silencing, including the formation of heterochromatin, silent chromosome territories, and repressed gene promoters, acts to stabilize patterns of gene regulation and the physical structure of the genome. Reduction of chromatin-mediated silencing can result in genome rearrangements...

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Bibliografiske detaljer
Udgivet i:Epigenetics
Main Authors: Valori, Virginia, Tus, Katalin, Laukaitis, Christina, Harris, David T., LeBeau, Lauren, Maggert, Keith A.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6961696/
https://ncbi.nlm.nih.gov/pubmed/31352858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2019.1649930
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