Epigenome-wide association study of DNA methylation and microRNA expression highlights novel pathways for human complex traits

DNA methylation (DNAm) and microRNAs (miRNAs) have been implicated in a wide-range of human diseases. While often studied in isolation, DNAm and miRNAs are not independent. We analyzed associations of expression of 283 miRNAs with DNAm at >400K CpG sites in whole blood obtained from 3565 individu...

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Detalhes bibliográficos
Publicado no:Epigenetics
Main Authors: Huan, Tianxiao, Mendelson, Michael, Joehanes, Roby, Yao, Chen, Liu, Chunyu, Song, Ci, Bhattacharya, Anindya, Rong, Jian, Tanriverdi, Kahraman, Keefe, Joshua, Murabito, Joanne M., Courchesne, Paul, Larson, Martin G., Freedman, Jane E., Levy, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6961684/
https://ncbi.nlm.nih.gov/pubmed/31282290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2019.1640547
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