Dynamic Role of trans Regulation of Gene Expression in Relation to Complex Traits

Identifying causal genetic variants and understanding their mechanisms of effect on traits remains a challenge in genome-wide association studies (GWASs). In particular, how genetic variants (i.e., trans-eQTLs) affect expression of remote genes (i.e., trans-eGenes) remains unknown. We hypothesized t...

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Detalhes bibliográficos
Publicado no:Am J Hum Genet
Main Authors: Yao, Chen, Joehanes, Roby, Johnson, Andrew D., Huan, Tianxiao, Liu, Chunyu, Freedman, Jane E., Munson, Peter J., Hill, David E., Vidal, Marc, Levy, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5384035/
https://ncbi.nlm.nih.gov/pubmed/28285768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2017.02.003
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