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Berberine Attenuates Hyperglycemia by Inhibiting the Hepatic Glucagon Pathway in Diabetic Mice

Dysregulated glucagon drives hyperfunction in hepatic glucose output, which is the main cause of persistent hyperglycemia in type 2 diabetes. Berberine (Zhang et al., 2010) has been used as a hypoglycemic agent, yet the mechanism by which BBR inhibits hepatic gluconeogenesis remains incompletely und...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Zhong, Ying, Jin, Jing, Liu, Peiyu, Song, Yu, Zhang, Hui, Sheng, Liang, Zhou, Huifang, Jiang, Bijie
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6961611/
https://ncbi.nlm.nih.gov/pubmed/31976031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/6210526
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