Amelioration of bleomycin-induced pulmonary fibrosis via TGF-β-induced Smad and non-Smad signaling pathways in galectin-9-deficient mice and fibroblast cells

BACKGROUND: Galectin-9 is a β-galactoside-binding protein with two carbohydrate recognition domains. Recent studies have revealed that galectin-9 regulates cellular biological reactions and plays a pivotal role in fibrosis. The aim of this study was to determine the role of galectin-9 in the pathoge...

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Publicat a:J Biomed Sci
Autors principals: Hsu, Yu-An, Chang, Ching-Yao, Lan, Joung-Liang, Li, Ju-Pi, Lin, Hui-Ju, Chen, Chih-Sheng, Wan, Lei, Liu, Fu-Tong
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6961390/
https://ncbi.nlm.nih.gov/pubmed/31937306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-020-0616-8
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