Lysine demethylase 2 (KDM2B) regulates hippo pathway via MOB1 to promote pancreatic ductal adenocarcinoma (PDAC) progression

BACKGROUND: Mps1 binding protein (MOB1) is one of the core components of the mammalian Hippo pathway and plays important roles in cancer development. However, its expression, function and regulation in pancreatic ductal adenocarcinoma (PDAC) have not been revealed yet. METHODS: The expression of MOB...

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Veröffentlicht in:J Exp Clin Cancer Res
Hauptverfasser: Quan, Ming, Chen, Zhiqin, Jiao, Feng, Xiao, Xiuying, Xia, Qing, Chen, Jingde, Chao, Qian, Li, Yandong, Gao, Yong, Yang, Haiyan, Wang, Liwei, Cui, Jiujie
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6961382/
https://ncbi.nlm.nih.gov/pubmed/31941533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1489-0
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