High glucose reduces expression of podocin in cultured human podocytes by stimulating TRPC6

The transient receptor potential canonical 6 (TRPC6) channel and podocin are colocalized in the glomerular slit diaphragm as an important complex to maintain podocyte function. Gain of TRPC6 function and loss of podocin function induce podocyte injury. We have previously shown that high glucose indu...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Am J Physiol Renal Physiol
Main Authors: Lu, Xiao-Yu, Liu, Bing-Chen, Cao, Yu-Ze, Song, Chang, Su, Hua, Chen, Guangping, Klein, Janet D., Zhang, Hui-Xue, Wang, Li-Hua, Ma, He-Ping
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2019
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6960785/
https://ncbi.nlm.nih.gov/pubmed/31566428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00215.2019
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki