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An update on the molecular pathogenesis and potential therapeutic targeting of AML with t(8;21)(q22;q22.1);RUNX1-RUNX1T1

Acute myeloid leukemia (AML) with t(8;21)(q22;q22.1);RUNX1-RUNX1T1, one of the core-binding factor leukemias, is one of the most common subtypes of AML with recurrent genetic abnormalities and is associated with a favorable outcome. The translocation leads to the formation of a pathological RUNX1-RU...

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Dettagli Bibliografici
Pubblicato in:Blood Adv
Autori principali: Al-Harbi, Sayer, Aljurf, Mahmoud, Mohty, Mohamad, Almohareb, Fahad, Ahmed, Syed Osman Ali
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6960481/
https://ncbi.nlm.nih.gov/pubmed/31935293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019000168
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