E(μ) and 3′RR transcriptional enhancers of the IgH locus cooperate to promote c-myc–induced mature B-cell lymphomas

Numerous B-cell lymphomas feature translocations linking oncogenes to different locations in the immunoglobulin heavy chain (IgH) locus. During Burkitt lymphoma (BL), IgH breakpoints for c-myc translocation stand either close to J(H) segments or within switch regions. Transcription, accessibility, a...

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Ghazzaui, Nour, Issaoui, Hussein, Ferrad, Mélissa, Carrion, Claire, Cook-Moreau, Jeanne, Denizot, Yves, Boyer, François
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2020
Assuntos:
Lymphoid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6960469/
https://ncbi.nlm.nih.gov/pubmed/31899800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019000845
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