Mouse Models of c-myc Deregulation Driven by IgH Locus Enhancers as Models of B-Cell Lymphomagenesis

Chromosomal translocations linking various oncogenes to transcriptional enhancers of the immunoglobulin heavy chain (IgH) locus are often implicated as the cause of B-cell malignancies. Two major IgH transcriptional enhancers have been reported so far. The E(μ) enhancer located upstream of the C(μ)...

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Vydáno v:Front Immunol
Hlavní autoři: Ferrad, Melissa, Ghazzaui, Nour, Issaoui, Hussein, Cook-Moreau, Jeanne, Denizot, Yves
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7390917/
https://ncbi.nlm.nih.gov/pubmed/32793219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01564
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