Clinical response to larotrectinib in adult Philadelphia chromosome–like ALL with cryptic ETV6-NTRK3 rearrangement

Philadelphia chromosome (Ph)–like acute lymphoblastic leukemia (ALL) is a subtype of Ph-negative ALL that molecularly resembles Ph-positive ALL. It shares the adverse prognosis of Ph-positive ALL, but lacks the BCR-ABL1 fusion oncogene. Instead, Ph-like ALL is associated with alternative mutations i...

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Dades bibliogràfiques
Publicat a:Blood Adv
Autors principals: Nardi, Valentina, Ku, Nora, Frigault, Matthew J., Dubuc, Adrian M., Tsai, Harrison Kwei, Amrein, Philip C., Hobbs, Gabriela S., Brunner, Andrew M., Narayan, Rupa, Burke, Meghan E., Foster, Julia, Dal Cin, Paola, Maus, Marcela V., Fathi, Amir T., Hock, Hanno
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2020
Matèries:
Exceptional Case Report
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6960464/
https://ncbi.nlm.nih.gov/pubmed/31905241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019000769
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