Clinical response to larotrectinib in adult Philadelphia chromosome–like ALL with cryptic ETV6-NTRK3 rearrangement

Philadelphia chromosome (Ph)–like acute lymphoblastic leukemia (ALL) is a subtype of Ph-negative ALL that molecularly resembles Ph-positive ALL. It shares the adverse prognosis of Ph-positive ALL, but lacks the BCR-ABL1 fusion oncogene. Instead, Ph-like ALL is associated with alternative mutations i...

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Nardi, Valentina, Ku, Nora, Frigault, Matthew J., Dubuc, Adrian M., Tsai, Harrison Kwei, Amrein, Philip C., Hobbs, Gabriela S., Brunner, Andrew M., Narayan, Rupa, Burke, Meghan E., Foster, Julia, Dal Cin, Paola, Maus, Marcela V., Fathi, Amir T., Hock, Hanno
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2020
Assuntos:
Exceptional Case Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6960464/
https://ncbi.nlm.nih.gov/pubmed/31905241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019000769
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