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The GTPase Rab39a promotes phagosome maturation into MHC‐I antigen‐presenting compartments

For CD8 T lymphocytes to mount responses to cancer and virally‐infected cells, dendritic cells must capture antigens present in tissues and display them as peptides bound to MHC‐I molecules. This is most often accomplished through a pathway called antigen cross‐presentation (XPT). Here, we report th...

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Bibliografiske detaljer
Udgivet i:EMBO J
Main Authors: Cruz, Freidrich M, Colbert, Jeff D, Rock, Kenneth L
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6960445/
https://ncbi.nlm.nih.gov/pubmed/31821587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2019102020
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