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The biology and underlying mechanisms of cross-presentation of exogenous antigens on MHC I molecules

To monitor the health of cells, the immune system tasks antigen presenting cells with gathering antigens from other cells and reporting them to CD8 T cells in the form of peptides bound to MHC I molecules. Most cells would be unable to perform this function because they use their MHC I molecules to...

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Bibliographische Detailangaben
Veröffentlicht in:Annu Rev Immunol
Hauptverfasser: Cruz, Freidrich M., Colbert, Jeff D., Merino, Elena, Kriegsman, Barry A., Rock, Kenneth L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5508990/
https://ncbi.nlm.nih.gov/pubmed/28125356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-immunol-041015-055254
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