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AMOT130 drives BMP-SMAD signaling at the apical membrane in polarized cells

The large isoform of the transmembrane protein angiomotin (AMOT130) controls cell proliferation and migration of many cell types. AMOT130 associates to the actin cytoskeleton and regulates tight-junction maintenance and signaling often via endosomal uptake of polarity proteins at tight junctions. AM...

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Bibliografiska uppgifter
I publikationen:Mol Biol Cell
Huvudupphovsmän: Brunner, Patrizia, Hastar, Nurcan, Kaehler, Christian, Burdzinski, Wiktor, Jatzlau, Jerome, Knaus, Petra
Materialtyp: Artigo
Språk:Inglês
Publicerad: The American Society for Cell Biology 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6960409/
https://ncbi.nlm.nih.gov/pubmed/31800378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E19-03-0179
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