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AMOT130 drives BMP-SMAD signaling at the apical membrane in polarized cells

The large isoform of the transmembrane protein angiomotin (AMOT130) controls cell proliferation and migration of many cell types. AMOT130 associates to the actin cytoskeleton and regulates tight-junction maintenance and signaling often via endosomal uptake of polarity proteins at tight junctions. AM...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Brunner, Patrizia, Hastar, Nurcan, Kaehler, Christian, Burdzinski, Wiktor, Jatzlau, Jerome, Knaus, Petra
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6960409/
https://ncbi.nlm.nih.gov/pubmed/31800378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E19-03-0179
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