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Monitoring online biomass with a capacitance sensor during scale-up of industrially relevant CHO cell culture fed-batch processes in single-use bioreactors

In 2004, the FDA published a guideline to implement process analytical technologies (PAT) in biopharmaceutical processes for process monitoring to gain process understanding and for the control of important process parameters. Viable cell concentration (VCC) is one of the most important key performa...

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Detalhes bibliográficos
Publicado no:Bioprocess Biosyst Eng
Main Authors: Metze, S., Ruhl, S., Greller, G., Grimm, C., Scholz, J.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6960217/
https://ncbi.nlm.nih.gov/pubmed/31549309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00449-019-02216-4
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