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Aberrantly High Levels of Somatic LINE-1 Expression and Retrotransposition in Human Neurological Disorders

Retrotransposable elements (RTEs) have actively multiplied over the past 80 million years of primate evolution, and as a consequence, such elements collectively occupy ∼ 40% of the human genome. As RTE activity can have detrimental effects on the human genome and transcriptome, silencing mechanisms...

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Bibliografski detalji
Izdano u:Front Genet
Glavni autori: Terry, Diane M., Devine, Scott E.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6960195/
https://ncbi.nlm.nih.gov/pubmed/31969897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.01244
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