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Transcriptome Profiling of Bovine Macrophages Infected by Mycobacterium avium spp. paratuberculosis Depicts Foam Cell and Innate Immune Tolerance Phenotypes

Mycobacterium avium spp. paratuberculosis (MAP) is the causative agent of Johne's disease (JD), also known as paratuberculosis, in ruminants. The mechanisms of JD pathogenesis are not fully understood, but it is known that MAP subverts the host immune system by using macrophages as its primary...

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Bibliographische Detailangaben
Veröffentlicht in:Front Immunol
Hauptverfasser: Ariel, Olivier, Gendron, Daniel, Dudemaine, Pier-Luc, Gévry, Nicolas, Ibeagha-Awemu, Eveline M., Bissonnette, Nathalie
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6960179/
https://ncbi.nlm.nih.gov/pubmed/31969876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02874
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