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Transcriptome Profiling of Bovine Macrophages Infected by Mycobacterium avium spp. paratuberculosis Depicts Foam Cell and Innate Immune Tolerance Phenotypes

Mycobacterium avium spp. paratuberculosis (MAP) is the causative agent of Johne's disease (JD), also known as paratuberculosis, in ruminants. The mechanisms of JD pathogenesis are not fully understood, but it is known that MAP subverts the host immune system by using macrophages as its primary...

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Bibliografische gegevens
Gepubliceerd in:Front Immunol
Hoofdauteurs: Ariel, Olivier, Gendron, Daniel, Dudemaine, Pier-Luc, Gévry, Nicolas, Ibeagha-Awemu, Eveline M., Bissonnette, Nathalie
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6960179/
https://ncbi.nlm.nih.gov/pubmed/31969876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02874
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