BICP0 Negatively Regulates TRAF6-Mediated NF-κB and Interferon Activation by Promoting K48-Linked Polyubiquitination of TRAF6

The infected cell protein 0 (BICP0) is an immediate early protein encoded by BHV-1, and its RING finger domain, which endows BICP0 with intrinsic E3 ubiquitin ligase activity, is common in all ICP0 proteins. Tumor necrosis factor receptor-associated factor 6 (TRAF6) is one of the TRAF family members...

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Bibliographic Details
Published in:Front Microbiol
Main Authors: Cao, Chong, An, Ran, Yu, YueYang, Dai, HaiYue, Qu, ZheHui, Gao, MingChun, Wang, JunWei
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020
Subjects:
Microbiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6960150/
https://ncbi.nlm.nih.gov/pubmed/31969874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2019.03040
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