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Siva-1 Promotes K-48 Polyubiquitination of TRAF2 and Inhibits TCR-Mediated Activation of NF-kappaB

The proapoptotic protein Siva-1 plays an important role in some of the extrinsic and intrinsic apoptosis signaling pathways in cancer cells. Previously, we showed that Siva-1 inhibited the activity of the prosurvival transcription factor NF-κB. In the present study, upon TCR cross-linking of Jurkat...

詳細記述

保存先:
書誌詳細
出版年:J Environ Pathol Toxicol Oncol
主要な著者: Gudi, Radhika, Barkinge, John, Hawkins, Sarah, Prabhakar, Bellur, Kanteti, Prasad
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4450717/
https://ncbi.nlm.nih.gov/pubmed/19392652
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