Učitavanje...
Duodenum Intestine-Chip for preclinical drug assessment in a human relevant model
Induction of intestinal drug metabolizing enzymes can complicate the development of new drugs, owing to the potential to cause drug-drug interactions (DDIs) leading to changes in pharmacokinetics, safety and efficacy. The development of a human-relevant model of the adult intestine that accurately p...
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| Izdano u: | eLife |
|---|---|
| Glavni autori: | , , , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
eLife Sciences Publications, Ltd
2020
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6959988/ https://ncbi.nlm.nih.gov/pubmed/31933478 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.50135 |
| Oznake: |
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