טוען...
Expression, Purification, and Characterization of Engineered Antibody CH2 and VH Domains
Most of the FDA-approved therapeutic monoclonal antibodies are full-size IgG molecules with a molecular weight of about 150 kDa. A major problem for such large molecules is their poor penetration into tissues (e.g., solid tumors) and poor or absent binding to regions on the surface of some molecules...
שמור ב:
| הוצא לאור ב: | Methods Mol Biol |
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| Main Authors: | , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2012
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6959533/ https://ncbi.nlm.nih.gov/pubmed/22735948 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-61779-921-1_6 |
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