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Engineered antibody CH2 domains binding to nucleolin: Isolation, characterization and improvement of aggregation

Smaller recombinant antibody fragments are now emerging as alternatives of conventional antibodies. Especially, immunoglobulin (Ig) constant CH2 domain and engineered CH2 with improved stability are promising as scaffolds for selection of specific binders to various antigens. We constructed a yeast...

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Detaylı Bibliyografya
Yayımlandı:Biochem Biophys Res Commun
Asıl Yazarlar: Li, Dezhi, Gong, Rui, Zheng, Jun, Chen, Xihai, Dimitrov, Dimiter S., Zhao, Qi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6957259/
https://ncbi.nlm.nih.gov/pubmed/28202413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2017.02.058
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