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Engineered antibody CH2 domains binding to nucleolin: Isolation, characterization and improvement of aggregation
Smaller recombinant antibody fragments are now emerging as alternatives of conventional antibodies. Especially, immunoglobulin (Ig) constant CH2 domain and engineered CH2 with improved stability are promising as scaffolds for selection of specific binders to various antigens. We constructed a yeast...
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| Publicat a: | Biochem Biophys Res Commun |
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| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6957259/ https://ncbi.nlm.nih.gov/pubmed/28202413 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2017.02.058 |
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