Establishing a model system for evaluating CAR T cell therapy using dogs with spontaneous diffuse large B cell lymphoma

Multiple rodent and primate preclinical studies have advanced CAR T cells into the clinic. However, no single model accurately reflects the challenges of effective CAR T therapy in human cancer patients. To evaluate the effectiveness of next-generation CAR T cells that aim to overcome barriers to du...

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Bibliographische Detailangaben
Veröffentlicht in:Oncoimmunology
Hauptverfasser: Panjwani, M. Kazim, Atherton, Matthew J., MaloneyHuss, Martha A., Haran, Kumudhini P., Xiong, Ailian, Gupta, Minnal, Kulikovsaya, Irina, Lacey, Simon F., Mason, Nicola J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2019
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6959441/
https://ncbi.nlm.nih.gov/pubmed/32002286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2019.1676615
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